As space becomes more crowded and missions venture further from Earth, spacecraft must make decisions independently, operate safely around hazards, and respond in real time. The Zero-G AstroLab was created to answer a critical question for the future of exploration: how do we build spacecraft that can think and act autonomously while protecting our planet? Founded and led by Dr Stefania Soldini, the lab is a unique microgravity simulation facility that enables hardware-in-the-loop testing of guidance, navigation and control systems before flight. Home to the UK’s flattest floor and one of a kind in Europe, free-floating robotic platforms and high-precision motion capture, researchers recreate the physics of space to test spacecraft manoeuvres, rendezvous operations and asteroid landings in realistic conditions. The team develops intelligent CubeSats, autonomous proximity operations, and advanced algorithms for navigation around complex bodies such as asteroids. These capabilities support applications including active debris removal, in-orbit servicing, swarm robotics, and deep-space exploration. Through projects such as REMORA (REndezvous Mission for Orbital Reconstruction of Asteroids), a fleet of self-driving CubeSats designed to attach to and track asteroids, and partnerships with missions including the Japanese Aerospace Exploration Agency (JAXA)’s Hayabusa2, the NASA’s Double Asteroid Redirection Test, and the European Space Agency (ESA)’s Hera and Ramses missions, Liverpool research directly strengthens global planetary defence. By combining robotics, astrodynamics and autonomy, the Zero-G AstroLab ensures spacecraft are smarter, safer, and ready to operate wherever exploration takes us.